Magnesium has been shown in clinical trials to reduce the frequency and severity of migraine. Magnesium plays a vital role in energy production, muscle, and nerve function and may play a role in cortical spreading depression, which is an underlying migraine mechanism.
When choosing a magnesium supplement, it is important to choose one with good oral bioavailability. For this reason, Dr. Natbony recommends magnesium glycinate. This form of magnesium is chelated (meaning it is bound to an amino acid), which allows it to be better absorbed by our GI tract. Additionally, magnesium glycinate contains the amino acid glycine, which can have a calming effect. It can help with sleep and dizziness in those with vestibular migraine. The optimal dose of magnesium is 400-600mg per day.